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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAB
All Species:
49.09
Human Site:
T112
Identified Species:
83.08
UniProt:
P31946
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31946
NP_003395.1
246
28082
T112
K
Y
L
I
P
N
A
T
Q
P
E
S
K
V
F
Chimpanzee
Pan troglodytes
XP_528202
382
42115
S247
K
F
L
I
P
N
A
S
Q
A
E
S
K
V
F
Rhesus Macaque
Macaca mulatta
XP_001109676
245
27935
T111
K
Y
L
I
P
N
A
T
Q
P
E
S
K
V
F
Dog
Lupus familis
XP_852754
244
27832
T110
K
Y
L
I
P
N
A
T
Q
P
E
S
K
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
T112
K
Y
L
I
L
N
A
T
Q
A
E
S
K
V
F
Rat
Rattus norvegicus
P35213
246
28036
T112
K
Y
L
I
L
N
A
T
H
A
E
S
K
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518806
277
31320
T143
K
Y
L
I
L
N
A
T
Q
P
E
S
K
V
F
Chicken
Gallus gallus
Q5ZLQ6
244
27889
T110
K
Y
L
I
V
N
A
T
Q
P
E
S
K
V
F
Frog
Xenopus laevis
Q5XHK2
244
27740
T110
R
F
L
V
P
N
A
T
P
P
E
S
K
V
F
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
S110
K
Y
L
I
P
N
A
S
Q
A
E
S
K
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
S113
K
Y
L
I
P
K
A
S
N
P
E
S
K
V
F
Honey Bee
Apis mellifera
XP_391841
247
28058
S112
K
Y
L
I
P
K
A
S
N
A
E
S
K
V
F
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
G112
K
F
L
I
P
K
A
G
A
A
E
S
K
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
T115
S
H
L
I
P
S
A
T
T
G
E
S
K
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
99.5
99.1
N.A.
98.7
98.3
N.A.
88.4
97.1
87.4
90.6
N.A.
78.6
80.5
78.2
N.A.
Protein Similarity:
100
60.7
99.5
99.1
N.A.
99.1
98.7
N.A.
88.4
98.7
94.3
96.3
N.A.
89.5
90.2
87.5
N.A.
P-Site Identity:
100
80
100
100
N.A.
86.6
80
N.A.
93.3
93.3
73.3
86.6
N.A.
80
73.3
66.6
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
86.6
80
N.A.
93.3
93.3
93.3
93.3
N.A.
86.6
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
59.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
100
0
8
43
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% E
% Phe:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
86
0
0
0
0
22
0
0
0
0
0
0
100
0
0
% K
% Leu:
0
0
100
0
22
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
72
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
72
0
0
0
8
50
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
29
0
0
0
100
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
65
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _